作者
C Nebot, P Regal, J Miranda, A Cepeda, C Fente
发表日期
2012/5/1
期刊
Journal of chromatographic science
卷号
50
期号
5
页码范围
414-425
出版商
Oxford University Press
简介
Veterinary drugs are widely and legally used to treat and prevent disease in livestock. However, drugs are also used illegally as growth-promoting agents. To protect the health of consumers, maximum residue limits (MRL) in food of animal origin have been established and are listed in Regulation 37/2010. According to this regulation, more than 300 drugs need to be controlled regularly in laboratories for residues of veterinary drugs. A cost-effective analytical method is very important and explains why the development of multi-residual methods is becoming popular in laboratories.
The aim of this work is to describe a simple, rapid and economical high-performance liquid chromatography–tandem mass spectrometry method for the simultaneous identification and quantification of 21 veterinary drugs in pork muscle samples. The sample clean-up procedure is performed with acidified dichloromethane and …
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