作者
Giuseppe Losurdo, Antonella Marra, Endrit Shahini, Bruna Girardi, Floriana Giorgio, Annacinzia Amoruso, A Pisani, Domenico Piscitelli, Michele Barone, Mariabeatrice Principi, Alfredo Di Leo, E Ierardi
发表日期
2017/6
来源
Neurogastroenterology & Motility
卷号
29
期号
6
页码范围
e13028
简介
Background
A link between small intestinal bacterial overgrowth (SIBO) and celiac disease (CD) has been hypothesized.
Methods
Literature search was performed in main medical databases. Methods of analysis/inclusion criteria were based on Preferred Reporting Items for Systematic reviews and Meta‐Analyses recommendations. The end‐point was to estimate, by a pooled‐data analysis, SIBO prevalence in CD. Proportions/percentages and their 95% confidence intervals (CI) were calculated by inverse variance method, whereas odd ratios (OR) and their 95% CI were estimated, where available, based on the Mantel‐Haenszel method. Data were entered into the RevMan 5.3 software.
Key Results
Eleven articles fulfilled considered criteria. The pooled mean prevalence of SIBO in CD was 20% (95% CI of 10%‐30%). In comparison to asymptomatic controls, CD was associated to higher risk of SIBO, with an …
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G Losurdo, A Marra, E Shahini, B Girardi, F Giorgio… - Neurogastroenterology & Motility, 2017