作者
Mohamad Alkhouli, Tatiana Busu, Kuldeep Shah, Mohammed Osman, Fahad Alqahtani, Bryan Raybuck
发表日期
2018/12
期刊
JACC: Clinical Electrophysiology
卷号
4
期号
12
页码范围
1629-1637
出版商
American College of Cardiology Foundation
简介
Objectives
This study sought to assess the incidence and clinical impact of device related thrombus (DRT) following precautions left atrial appendage occlusion (LAAO).
Background
Device-related thrombus is a known complication of LAAO. However, data on the incidence of DRT and its impact on outcomes are limited.
Methods
The authors performed a meta-analysis of randomized and observational studies to calculate the pooled incidence of DRT and the pooled odds ratio (OR) of ischemic events in patients with DRT and those without DRT.
Results
In the 66 included studies; the incidence of DRT was 351/10, 153 (3.8%, range 0% to 17%, I2 = 56.8). The diagnosis was made in <90, 90 to 365, and >365 days in 42%, 57%, and 1% of patients, respectively. There was no difference in DRT rates between the AMPLATZER (AMPLATZER, AGA Medical Corporation, Golden Valley, Minnesota) and WATCHMAN …
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M Alkhouli, T Busu, K Shah, M Osman, F Alqahtani… - JACC: Clinical Electrophysiology, 2018