作者
Tomislav Mestrovic, Gisela Robles Aguilar, Lucien R Swetschinski, Kevin S Ikuta, Authia P Gray, Nicole Davis Weaver, Chieh Han, Eve E Wool, Anna Gershberg Hayoon, Simon I Hay, Christiane Dolecek, Benn Sartorius, Christopher JL Murray, Isaac Yeboah Addo, Bright Opoku Ahinkorah, Ayman Ahmed, Mamoon A Aldeyab, Kasim Allel, Robert Ancuceanu, Anayochukwu Edward Anyasodor, Marcel Ausloos, Fabio Barra, Akshaya Srikanth Bhagavathula, Dinesh Bhandari, Sonu Bhaskar, Natalia Cruz-Martins, Anna Dastiridou, Klara Dokova, Eleonora Dubljanin, Oyewole Christopher Durojaiye, Adeniyi Francis Fagbamigbe, Simone Ferrero, Peter Andras Gaal, Veer Bala Gupta, Vijai Kumar Gupta, Vivek Kumar Gupta, Claudiu Herteliu, Salman Hussain, Irena M Ilic, Milena D Ilic, Elham Jamshidi, Tamas Joo, Andre Karch, Adnan Kisa, Sezer Kisa, Tomislav Kostyanev, Hmwe Hmwe Kyu, Judit Lam, Graciliana Lopes, Alexander G Mathioudakis, Alexios-Fotios A Mentis, Irmina Maria Michalek, Mohammad Ali Moni, Catrin E Moore, Francesk Mulita, Ionut Negoi, Ruxandra Irina Negoi, Tamas Palicz, Adrian Pana, Joao Perdigao, Ionela-Roxana Petcu, Navid Rabiee, David Laith Rawaf, Salman Rawaf, Murad Ziyaudinovich Shakhmardanov, Aziz Sheikh, Luis Manuel Lopes Rodrigues Silva, Valentin Yurievich Skryabin, Anna Aleksandrovna Skryabina, Bogdan Socea, Andy Stergachis, Temenuga Zhekova Stoeva, Chandra Datta Sumi, Arulmani Thiyagarajan, Marcos Roberto Tovani-Palone, Metin Yesiltepe, Sojib Bin Zaman, Mohsen Naghavi
发表日期
2022/11/1
期刊
The Lancet Public Health
卷号
7
期号
11
页码范围
e897-e913
出版商
Elsevier
简介
Background
Antimicrobial resistance (AMR) represents one of the most crucial threats to public health and modern health care. Previous studies have identified challenges with estimating the magnitude of the problem and its downstream effect on human health and mortality. To our knowledge, this study presents the most comprehensive set of regional and country-level estimates of AMR burden in the WHO European region to date.
Methods
We estimated deaths and disability-adjusted life-years attributable to and associated with AMR for 23 bacterial pathogens and 88 pathogen–drug combinations for the WHO European region and its countries in 2019. Our methodological approach consisted of five broad components: the number of deaths in which infection had a role, the proportion of infectious deaths attributable to a given infectious syndrome, the proportion of infectious syndrome deaths attributable to a given …
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