作者
Abdelhalim Elshiekh, Sivaniya Subramaniapillai, Sricharana Rajagopal, Stamatoula Pasvanis, Elizabeth Ankudowich, M Natasha Rajah
发表日期
2020/8/1
期刊
Cortex
卷号
129
页码范围
296-313
出版商
Elsevier
简介
Remembering associations between encoded items and their contextual setting is a feature of episodic memory. Although this ability generally deteriorates with age, there is substantial variability in how older individuals perform on episodic memory tasks. A current topic of debate in the cognitive neuroscience of aging literature revolves around whether this variability may stem from genetic and/or environmental factors related to reserve, allowing some individuals to compensate for age-related decline through differential recruitment of brain regions. In this fMRI study spanning a large adult lifespan sample (N = 154), we tested whether higher cognitive reserve was associated with better task-fMRI context memory performance, and functional compensatory activity patterns in the aging brain. We used multivariate Behaviour Partial Least Squares (B-PLS) analysis to examine how age, retrieval accuracy, and a proxy …
引用总数
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