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Background:

Explanatory models represent patient understanding of etiology, pathophysiology, illness, symptoms, and treatments, but little attention has been paid to how they are used by patients “at risk” for future disease.

Objective:

The aims of this study were to elucidate what constitutes an explanatory model of risk and to describe explanatory models of risk related to developing breast cancer.

Methods:

Thirty qualitative interviews with women identified as at an increased risk for breast cancer were conducted. Interviews were coded to identify domains of explanatory models of risk using a priori codes derived from the explanatory model of illness framework. Within each domain, a grounded thematic analysis described participants’ explanatory models related to breast cancer risk.

Results:

The domains of treatment and etiology remained similar in a risk context compared with illness, whereas course of illness …