作者
Dillon C Adam, Peng Wu, Jessica Y Wong, Eric HY Lau, Tim K Tsang, Simon Cauchemez, Gabriel M Leung, Benjamin J Cowling
发表日期
2020/11
期刊
Nature Medicine
卷号
26
期号
11
页码范围
1714-1719
出版商
Nature Publishing Group US
简介
Superspreading events (SSEs) have characterized previous epidemics of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) infections, , , , –. For SARS-CoV-2, the degree to which SSEs are involved in transmission remains unclear, but there is growing evidence that SSEs might be a typical feature of COVID-19,. Using contact tracing data from 1,038 SARS-CoV-2 cases confirmed between 23 January and 28 April 2020 in Hong Kong, we identified and characterized all local clusters of infection. We identified 4–7 SSEs across 51 clusters (n = 309 cases) and estimated that 19% (95% confidence interval, 15–24%) of cases seeded 80% of all local transmission. Transmission in social settings was associated with more secondary cases than households when controlling for age (P = 0.002). Decreasing the delay between symptom onset …
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