作者
Premika SW Boedhoe, Daan van Rooij, Martine Hoogman, Jos WR Twisk, Lianne Schmaal, Yoshinari Abe, Pino Alonso, Stephanie H Ameis, Anatoly Anikin, Alan Anticevic, Philip Aherson, Celso Arango, Paul D Arnold, Francesca Assogna, Guillaume Auzias, Tobias Banaschewski, Alexander Baranov, Marcelo C Batistuzzo, Sarah Baumeister, Ramona Baur-Streubel, Marlene Behrmann, Mark A Bellgrove, Francesco Benedetti, Jan C Beucke, Joseph Biederman, Irene Bollettini, Anushree Bose, Janita Bralten, Ivanei E Bramati, Daniel Brandeis, Silvia Brem, Brian P Brennan, Geraldo F Busatto, Sara Calderoni, Anna Calvo, Rosa Calvo, Francisco X Castellanos, Mara Cercignani, Tiffany M Chaim-Avancini, Kaylita C Chantiluke, Yuqi Cheng, Kang Ik K Cho, Anastasia Christakou, David Coghill, Annette Conzelmann, Ana I Cubillo, Anders M Dale, Sara Dallaspezia, Eileen Daly, Damiaan Denys, Christine Deruelle, Adriana Di Martino, Ilan Dinstein, Alysa E Doyle, Sarah Durston
发表日期
2020
期刊
American Journal of Psychiatry
卷号
177
期号
9
页码范围
834-843
出版商
American Psychiatric Association
简介
Objective
Attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and obsessive-compulsive disorder (OCD) are common neurodevelopmental disorders that frequently co-occur. The authors sought to directly compare these disorders using structural brain imaging data from ENIGMA consortium data.
Methods
Structural T1-weighted whole-brain MRI data from healthy control subjects (N=5,827) and from patients with ADHD (N=2,271), ASD (N=1,777), and OCD (N=2,323) from 151 cohorts worldwide were analyzed using standardized processing protocols. The authors examined subcortical volume, cortical thickness, and cortical surface area differences within a mega-analytical framework, pooling measures extracted from each cohort. Analyses were performed separately for children, adolescents, and adults, using linear mixed-effects models adjusting for age, sex, and site (and intracranial …
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