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Effective role of optical duobinary transmitter with optical coherent quadrature amplitude modulation (QAM) receiver based on light amplifiers measured is stimulated by using optisystem simulation software version 13. Signal, noise power levels are stimulated after long haul fiber optic range up to 350 km distance. Measured light amplifiers, optical duobinary transmitters and optical QAM receiver are employed to measure the peak signal amplitude power (SAP) and noise signal power for bit rate transmission with 100 Gb/s based 350 km length. Maximum signal power level margin is enhanced with high data rates transmission.