作者
Susan Whitfield-Gabrieli, Carter Wendelken, Alfonso Nieto-Castañón, Stephen Kent Bailey, Sheeba Arnold Anteraper, Yoon Ji Lee, Xiao-qian Chai, Dina R Hirshfeld-Becker, Joseph Biederman, Laurie E Cutting, Silvia A Bunge
发表日期
2020/4/1
期刊
JAMA psychiatry
卷号
77
期号
4
页码范围
378-386
出版商
American Medical Association
简介
Importance
Understanding the neurodevelopmental trajectory of psychiatric symptoms is important for improving early identification, intervention, and prevention of mental disorders.
Objective
To test whether the strength of the coupling of activation between specific brain regions, as measured by resting-state functional magnetic resonance imaging (fMRI), predicted individual children’s developmental trajectories in terms of attentional problems characteristic of attention-deficit/hyperactivity disorder and internalizing problems characteristics of major depressive disorder (MDD).
Design, Setting, and Participants
A community cohort of 94 children was recruited from Vanderbilt University between 2010 and 2013. They were followed up longitudinally for 4 years and the data were analyzed from 2016 to 2019. Based on preregistered hypotheses and an analytic plan, we examined whether specific brain connectivity …
学术搜索中的文章
S Whitfield-Gabrieli, C Wendelken, A Nieto-Castañón… - JAMA psychiatry, 2020