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A new current mode building block named voltage and current gain second generation current conveyor (VCG-CCII) is introduced. The voltage and current buffers of the standard CCII are replaced by voltage and current amplifiers with tunable gains so to obtain an extremely flexible and versatile building block. The VCG-CCII can be used in place of the standard CCII in impedance conversion applications so to utilize only one active component. A circuit implementation in a standard 0.35 μm CMOS process is presented and used to multiply, as an example, a 10 pF capacitor by a factor tunable from 1 up to about 3100, achieving a capacitance multiplication for more than 6 decades frequency range (from 0.15 to 865 KHz for the highest multiplication factor).