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Advances in artificial intelligence (AI) are increasingly enabling firms to develop services that utilize autonomous vehicles (AVs). Yet, there are significant psychological barriers to adoption, and insights from extant literature are insufficient to understand customer emotions regarding AV services. To allow for a holistic exploration of customer perspectives, we synthesize multidisciplinary literature to develop the Customer Responses to Unmanned Intelligent-transport Services based on Emotions (CRUISE) framework, which lays the foundation for improved strategizing, targeting, and positioning of AV services. We subsequently provide empirical support for several propositions underpinning the CRUISE framework using representative multinational panel data (N = 27,565) and an implicit association test (N = 300). We discover four distinct customer segments based on their preferred degree of service autonomy and …