作者
Andrea Di Nisio, Iva Sabovic, Umberto Valente, Simone Tescari, Maria Santa Rocca, Diego Guidolin, Stefano Dall’Acqua, Laura Acquasaliente, Nicola Pozzi, Mario Plebani, Andrea Garolla, Carlo Foresta
发表日期
2019/4
期刊
The Journal of Clinical Endocrinology & Metabolism
卷号
104
期号
4
页码范围
1259-1271
出版商
Endocrine Society
简介
Background
Considerable attention has been paid to perfluoroalkyl compounds (PFCs) because of their worldwide presence in humans, wildlife, and environment. A wide variety of toxicological effects is well supported in animals, including testicular toxicity and male infertility. For these reasons, the understanding of epidemiological associations and of the molecular mechanisms involved in the endocrine-disrupting properties of PFCs on human reproductive health is a major concern.
Objective
To investigate the relationship between PFC exposure and male reproductive health.
Design
This study was performed within a screening protocol to evaluate male reproductive health in high schools.
Patients
This is a cross-sectional study on 212 exposed males from the Veneto region, one of the four areas worldwide heavily polluted with …
学术搜索中的文章
A Di Nisio, I Sabovic, U Valente, S Tescari, MS Rocca… - The Journal of Clinical Endocrinology & Metabolism, 2019