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Objective:

Clinical trials have indicated that water-soluble fiber from oats reduces serum cholesterol among hypercholesterolemic patients on a low-fat diet. We examined the effect of dietary fiber intake on serum lipids among persons without hypercholesterolemia.

Design:

Randomized controlled trial.

Setting and subjects:

We recruited 110 participants who were aged 30–65 years and had a serum cholesterol level< 240 mg/dl from community.

Intervention:

Study participants were randomly assigned to receive 8 g per day of water-soluble fiber from oat bran or a control intervention.

Results:

At baseline, the mean levels of serum cholesterol and other measured variables were comparable between the high-fiber and control groups. Over the 3-month intervention, mean changes (95% confidence interval (CI)) in total, HDL-, and LDL-cholesterol were− 2.42 mg/dl (− 8.90 to 4.05 mg/dl; P= 0.46),− 0.24 mg/dl (− 2.19 to 1.71 mg …