作者
Aseem K Tiwari, Prashant Pandey, Jyoti Sharma, Kumari Shailja, Surbhi Dixit, Vimarsh Raina
发表日期
2014/4/1
期刊
Transfusion and Apheresis Science
卷号
50
期号
2
页码范围
230-234
出版商
Pergamon
简介
Introduction
Since there is scarce data available on incidence and type of irregular antibodies in patients and donors in India, a study was undertaken to find the incidence of irregular antibodies in patients and irregular antibodies and a positive Direct Antiglobulin Test (DAT) in blood donors.
Materials and methods
Antibody screening was performed using commercial pooled “O” cells and three-cell panel for donors and patients respectively and an 11-cell panel for identification using Column Agglutination Technology (CAT) with Low-Ionic-Strength Saline–Indirect Antiglobulin Test (LISS–IAT) technique (Ortho Clinical Diagnostics, Johnson & Johnson, USA). The cassettes used were Anti-human Globulin (AHG) type. DAT on donors was also performed using the AHG cassettes.
Results
Cumulative incidence of irregular antibodies amongst patients (n = 32,560) and donors (n = 31,367) were 0.12–0.009%, respectively …
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