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Objective:

To assess the utility of full bowel preparation with oral nonabsorbable antibiotics in preventing infectious complications after elective colectomy.

Background:

Bowel preparation before elective colectomy remains controversial. We hypothesize that mechanical bowel preparation with nonabsorbable oral antibiotics is associated with a decreased rate of postoperative infectious complications when compared with no bowel preparation.

Methods:

Patient and clinical data were obtained from the Michigan Surgical Quality Collaborative–Colectomy Best Practices Project. Propensity score analysis was used to match elective colectomy cases based on primary exposure variable—full bowel preparation (mechanical bowel preparation with nonabsorbable oral antibiotics) or no bowel preparation (neither mechanical bowel preparation given nor nonabsorbable oral antibiotic given). The primary outcomes for this study …