作者
Rocco A Montone, Leonarda Galiuto, Maria Chiara Meucci, Marco Giuseppe Del Buono, Federico Vergni, Massimiliano Camilli, Tommaso Sanna, Daniela Pedicino, Antonino Buffon, Domenico D'Amario, Luca Giraldi, Carlo Trani, Giovanna Liuzzo, Antonio G Rebuzzi, Giampaolo Niccoli, Filippo Crea
发表日期
2020/6/1
期刊
Heart
卷号
106
期号
12
页码范围
923-930
出版商
BMJ Publishing Group Ltd and British Cardiovascular Society
简介
Objective
Patients with Takotsubo syndrome (TTS) present an acute microvascular dysfunction that leads to an impaired myocardial perfusion and, in more severe forms, an impaired epicardial flow. However, clinical relevance of a delayed coronary flow, the coronary slow flow (CSF), has never been investigated. We studied the prognostic value of CSF occurring in the acute phase of TTS.
Methods
This cohort study prospectively evaluated patients with a diagnosis of TTS. CSF was defined as angiographically non-obstructive coronary arteries with thrombolysis in myocardial infarction-2 flow. The incidence of overall mortality and major adverse cardiovascular events (MACEs), defined as the composite of TTS recurrence, cardiac rehospitalisation, cerebrovascular events and mortality, was assessed at follow-up.
Results
We enrolled 101 patients (mean age 71.0±11.1 years, 86 (85.1%) female); CSF occurred in 18 (17.8 …
学术搜索中的文章
RA Montone, L Galiuto, MC Meucci, MG Del Buono… - Heart, 2020