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In this contribution, we introduce an interference alignment scheme that allows the coexistence of an orthogonal frequency division multiplexing (OFDM) macro-cell and a cognitive small-cell, deployed in a two-tiered structure and transmitting over the same bandwidth. We derive the optimal linear strategy for the single antenna secondary base station, maximizing the spectral efficiency of the opportunistic link, accounting for both signal sub-space structure and power loading strategy. Our analytical and numerical findings prove that the precoder structure proposed is optimal for the considered scenario in the face of Rayleigh and exponential decaying channels.