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The aim of this systematic review and meta-analysis study was to estimate the pooled prevalence of burnout among health care workers (HCWs), who worked in health centers during the coronavirus disease (COVID-19) outbreak, based on the Maslach Burnout Inventory (MBI) Questionnaire. A comprehensive search based on specific terms was performed through the online studies of Pubmed, Scopus, Web of Science, and ProQuest, until January 2022. The methodological quality of included studies was assessed using the National Institutes of Health (NIH) tool. Data analysis was carried out through the random-effects model, and the heterogeneity was investigated by I² statistic using the software STATA Version 16. In total, seven articles with 5,022 participants were included in the final analysis. Four studies with 4,419 participants reported the prevalence of burnout as percent in moderate and severe types for all …