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To determine if non-invasive oxygenation indices, namely peripheral capillary oxygen saturation (S_pO₂)/fraction of inspired oxygen (F_iO₂) and partial pressure of alveolar oxygen (P_AO₂)/F_iO₂ may be used as effective surrogates for the partial pressure of arterial oxygen (P_aO₂)/F_iO₂. Also, to determine the S_pO₂/F_iO₂ and P_AO₂/F_iO₂ values that correspond to P_aO₂/F_iO₂ thresholds for identifying acute respiratory distress syndrome (ARDS) in patients following coronary artery bypass graft (CABG) surgery.

A prospective derivation-validation cohort study in the Open-Heart ICU of an academic teaching hospital. Recorded variables included patient demographics, ventilator settings, chest radiograph results, and S_PO₂, P_aO₂, P_AO_2, S_aO₂, and F_iO₂. Linear regression modeling was used to quantify the relationship between indices …