作者
Christos V Bourantas, Michail I Papafaklis, Anna Kotsia, Vasim Farooq, Takashi Muramatsu, Josep Gomez-Lara, Yao-Jun Zhang, Javaid Iqbal, Fanis G Kalatzis, Katerina K Naka, Dimitrios I Fotiadis, Cecile Dorange, Jin Wang, Richard Rapoza, Hector M Garcia-Garcia, Yoshinobu Onuma, Lampros K Michalis, Patrick W Serruys
发表日期
2014/3
期刊
JACC: Cardiovascular Interventions
卷号
7
期号
3
页码范围
315-324
出版商
American College of Cardiology Foundation
简介
Objectives
This study sought to investigate the effect of endothelial shear stress (ESS) on neointimal formation following an Absorb bioresorbable vascular scaffold (BVS) (Abbott Vascular, Santa Clara, California) implantation.
Background
Cumulative evidence, derived from intravascular ultrasound–based studies, has demonstrated a strong association between local ESS patterns and neointimal formation in bare-metal stents, whereas in drug-eluting stents, there are contradictory data about the effect of ESS on the vessel wall healing process. The effect of ESS on neointimal development following a bioresorbable scaffold implantation remains unclear.
Methods
Twelve patients with an obstructive lesion in a relatively straight arterial segment, who were treated with an Absorb BVS and had serial optical coherence tomographic examination at baseline and 1-year follow-up, were included in the current analysis. The …
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CV Bourantas, MI Papafaklis, A Kotsia, V Farooq… - JACC: Cardiovascular Interventions, 2014