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Computerized healthcare has undergone rapid development thanks to the advances in medical imaging and machine learning technologies. Especially, recent progress on deep learning opens a new era for multimedia based clinical decision support. In this paper, we use deep learning with brain network and clinical relevant text information to make early diagnosis of Alzheimer's Disease (AD). The clinical relevant text information includes age, gender, and $ApoE$ gene of the subject. The brain network is constructed by computing the functional connectivity of brain regions using resting-state functional magnetic resonance imaging (R-fMRI) data. A targeted autoencoder network is built to distinguish normal aging from mild cognitive impairment, an early stage of AD. The proposed method reveals discriminative brain network features effectively and provides a reliable classifier for AD detection. Compared to …