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Glioma is a relatively common brain tumor disease with high mortality rate. Humans have been seeking a more effective therapy. In the course of treatment, the specific location of the tumor needs to be determined first in any case. Therefore, how to segment tumors from brain tissue accurately and quickly is a persistent problem. In this paper, a new dual-stream decoding CNN architecture combined with U-net for automatic segmentation of brain tumor on MR images namely DDU-net is proposed. Two edge-based optimization strategies are used to enhance the performance of brain tumor segmentation. First, we design a separate branch to process edge stream information. Here, high level edge features are reduced in dimension of channel and integrated into the conventional semantic stream in the way of residual. Second, a regularization loss function is used to encourage the predicted segmentation mask to …