作者
Mary Ramsay, N Crowther, Ernest Tambo, Godfred Agongo, V Baloyi, S Dikotope, X Gómez-Olivé, N Jaff, Hermann Sorgho, R Wagner, C Khayeka-Wandabwa, A Choudhury, S Hazelhurst, K Kahn, Z Lombard, F Mukomana, C Soo, H Soodyall, A Wade, S Afolabi, I Agorinya, L Amenga-Etego, SA Ali, JD Bognini, RP Boua, C Debpuur, S Diallo, E Fato, A Kazienga, SZ Konkobo, PM Kouraogo, F Mashinya, L Micklesfield, S Nakanabo-Diallo, B Njamwea, E Nonterah, S Ouedraogo, V Pillay, AM Somande, P Tindana, R Twine, M Alberts, C Kyobutungi, SA Norris, AR Oduro, H Tinto, S Tollman, O Sankoh
发表日期
2016/1
期刊
Global health, epidemiology and genomics
卷号
1
页码范围
e20
出版商
Cambridge University Press
简介
Africa is experiencing a rapid increase in adult obesity and associated cardiometabolic diseases (CMDs). The H3Africa AWI-Gen Collaborative Centre was established to examine genomic and environmental factors that influence body composition, body fat distribution and CMD risk, with the aim to provide insights towards effective treatment and intervention strategies. It provides a research platform of over 10 500 participants, 40–60 years old, from Burkina Faso, Ghana, Kenya and South Africa. Following a process that involved community engagement, training of project staff and participant informed consent, participants were administered detailed questionnaires, anthropometric measurements were taken and biospecimens collected. This generated a wealth of demographic, health history, environmental, behavioural and biomarker data. The H3Africa SNP array will be used for genome-wide association studies …
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M Ramsay, N Crowther, E Tambo, G Agongo, V Baloyi… - Global health, epidemiology and genomics, 2016