作者
Lain-Yen Hu, Daniel Du, Jennifer Hoffman, Yvonne Smith, Victor Fedij, Catherine Kostlan, Theodore R Johnson, Yun Huang, Steve Kesten, William Harter, Wen Song Yue, Jie Jack Li, Nicole Barvian, Lorna Mitchell, Huangshu John Lei, Bruce Lefker, Mathew Carroll, Danielle Dettling, Teresa Krieger-Burke, Brian Samas, Radhika Yalamanchili, Kimberly Lapham, David Pocalyko, Drago Sliskovic, Susan Ciotti, Brenda Stoller, Mostofa A Hena, Qizhu Ding, Samarendra N Maiti, Michael Stier, Howard Welgus
发表日期
2007/11/1
期刊
Bioorganic & medicinal chemistry letters
卷号
17
期号
21
页码范围
5983-5988
出版商
Pergamon
简介
Synthesis, pharmacology, and pharmacokinetic profiles of (1R, 2S)-4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile are reported. This compound demonstrated remarkable potency for stimulating hair growth in a male C3H mouse model as well as reducing sebum production in the male Syrian hamster ear model.
学术搜索中的文章
LY Hu, D Du, J Hoffman, Y Smith, V Fedij, C Kostlan… - Bioorganic & medicinal chemistry letters, 2007