作者
Kathryn L Humphreys, Lucy S King, Matthew D Sacchet, M Catalina Camacho, Natalie L Colich, Sarah J Ordaz, Tiffany C Ho, Ian H Gotlib
发表日期
2019/5
期刊
Developmental Science
卷号
22
期号
3
页码范围
e12775
简介
Exposure to stress has been causally linked to changes in hippocampal volume (HV). Given that the hippocampus undergoes rapid changes in the first years of life, stressful experiences during this period may be particularly important in understanding individual differences in the development of the hippocampus. One hundred seventy‐eight early adolescents (ages 9–13 years; 43% male) were interviewed regarding exposure to and age of onset of experiences of stress; the severity of each stressful event was rated by an objective panel. All participants underwent structural magnetic resonance imaging, from which HVs were automatically segmented. Without considering the age of onset for stressful experiences, there was a small but statistically significant negative association of stress severity with bilateral HV. When considering the age of onset, there was a moderate and significant negative association …
引用总数
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