作者
Erica S Ghezzi, Tyler J Ross, Rhianna Sharman, Daniel Davis, Monique S Boord, Thivina Thanabalan, Jessica Thomas, Hannah AD Keage
发表日期
2022/1/1
来源
Neuroscience & Biobehavioral Reviews
卷号
132
页码范围
248-259
出版商
Pergamon
简介
Delirium is a common neurocognitive disorder in hospitalised older adults with substantial negative consequences. Impaired global cognition is a well-established delirium risk factor. However, poor performance on attention tests and higher intra-subject variability may be more sensitive delirium risk factors, given the disorder is characterised by a fluctuating course and attentional deficits. We systematically searched databases (Embase, PsycINFO, MEDLINE) and 44 studies satisfied inclusion criteria. Random-effects meta-analysis models showed poor performance in all cognitive domains except perception was significantly associated with incident delirium. Largest effects were for orientation (g=-1.20) and construction and motor performance (g=-0.60). These effects were no longer significant in the subgroup without pre-existing cognitive impairment, where executive functions and verbal functions and language …
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