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A probabilistic model to estimate the fatigue life of an additively manufactured material with polished surface was developed based on the statistical size distribution of grains and various manufacturing defects such as pores and unfused powder particles embedded in the microstructure. The probabilistic model includes the prospect of each microstructural feature to exist on the specimen surface and its potential impact on fatigue crack initiation through defect-grain interaction. The model was applied to as-built and peak-hardened Al-1.5Cu-0.8Sc-0.4Zr (wt.%) alloy developed by laser powder bed fusion. Bending fatigue experiments performed on both as-built and peak-hardened samples confirmed the trends predicted by the probabilistic model. The cumulative probability distribution plotted against fatigue life fitted well to a three-parameter Weibull distribution function. The indicator for the scatter in fatigue life from …