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The purposes are to explore the effect of Digital Twins (DTs) in Unmanned Aerial Vehicles (UAVs) on providing medical resources quickly and accurately during COVID-19 prevention and control. The feasibility of UAV DTs during COVID-19 prevention and control is analyzed. Deep Learning (DL) algorithms are introduced. A UAV DTs information forecasting model is constructed based on improved AlexNet, whose performance is analyzed through simulation experiments. As end-users and task proportion increase, the proposed model can provide smaller transmission delays, lesser energy consumption in throughput demand, shorter task completion time, and higher resource utilization rate under reduced transmission power than other state-of-art models. Regarding forecasting accuracy, the proposed model can provide smaller errors and better accuracy in Signal-to-Noise Ratio (SNR), bit quantizer, number of …