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Collaboration among logistics operators offers an effective way to improve customer service and freight transportation efficiency. One form of collaboration is the sharing of logistics resources (e.g., delivery vehicles). Existing studies on collaboration and resource sharing have not sufficiently accounted for the time frame within which collaboration happens, and they mostly assume that collaboration among logistics operators occurs in a single time period. This study addresses the issue of collaboration across multiple time periods, in which logistics resources can be shared between different service time periods, by formulating and solving a two-echelon collaborative multi-depot multi-period vehicle routing problem (2E-CMDPVRP). The 2E-CMDPVRP is formulated as a multi-objective integer programming model that minimizes logistics operational costs, service waiting times, and number of vehicles in multiple …