作者
Rosa M Valls, Anna Pedret, Lorena Calderón-Pérez, Elisabet Llauradó, Laura Pla-Pagà, Judit Companys, Ana Moragas, Francisco Martín-Luján, Yolanda Ortega, Montse Giralt, Marta Romeu, Laura Rubió, Jordi Mayneris-Perxachs, Núria Canela, Francesc Puiggrós, Antoni Caimari, Josep M Del Bas, Lluís Arola, Rosa Solà
发表日期
2021/4
期刊
European journal of nutrition
卷号
60
页码范围
1277-1288
出版商
Springer Berlin Heidelberg
简介
Purpose
To assess the sustained and acute effects, as well as the influence of sustained consumption on the acute effects, of orange juice (OJ) with a natural hesperidin content and hesperidin-enriched OJ (EOJ) on blood (BP) and pulse (PP) pressures in pre- and stage-1 hypertensive individuals.
Methods
In a randomized, parallel, double-blind, placebo-controlled trial, participants (n = 159) received 500 mL/day of control drink, OJ, or EOJ for 12 weeks. Two dose–response studies were performed at baseline and after 12 weeks.
Results
A single EOJ dose (500 mL) reduced systolic BP (SBP) and PP, with greater changes after sustained treatment where a decrease in diastolic BP (DBP) also occurred (P < 0.05). SBP and PP decreased in a dose-dependent manner relative to the hesperidin content of the beverages …
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RM Valls, A Pedret, L Calderón-Pérez, E Llauradó… - European journal of nutrition, 2021