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Babesiosis is an emerging tick-borne disease of cattle and domestic buffalo (Bubalus bubalis), caused by hemoparasite of genus Babesia and is prevalent all over the world. This disease has considerable economic, medical and veterinary impact (Roy, 1990). The hemoparasitic diseases threaten an estimated 250 million cattle and act as a major constraint on livestock production and improvement in many developing countries (Radostits et al., 2000).

Babesiosis is characterized by high fever and intravascular haemolysis, leading to anaemia, icterus, haemoglobinurea and death. Mortality is extremely variable and may be to 50% or higher, but in the absence of undue stress, with early and effective treatment, the mortality rate can be reduced to 5%(Mahoney, 1977). The greatest infection rate is seen in animals at 6-12 months of age. The average age at which calves in enzootic areas become infected is 11 weeks, but at this early age clinical signs and pathological changes are mild and short lived