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The prevalence of Balantidium coli in cattle from the River Ravi region of Lahore was examined and the efficacy of three treatments measured. A total of 200 fecal samples were collected from cattle and examined microscopically; 50 (25%) were positive for B. coli cysts. The final efficacy of treatment with metronidazole, oxytetracycline, or secnidazole was 37.5%, 62.5%, and 87.5%, respectively, making secnidazole the most effective.