作者
Jing Sun, Keri N Althoff, Yuezhou Jing, Michael A Horberg, Kate Buchacz, M John Gill, Amy C Justice, Charles S Rabkin, James J Goedert, Keith Sigel, Edward Cachay, Lesley Park, Joseph K Lim, H Nina Kim, Vincent Lo Re, Richard Moore, Timothy Sterling, Marion G Peters, Chad J Achenbach, Michael Silverberg, Jennifer E Thorne, Angel M Mayor, Heidi M Crane, Mari M Kitahata, Marina Klein, Gregory D Kirk
发表日期
2021/2/1
期刊
JAMA network open
卷号
4
期号
2
页码范围
e2037512-e2037512
出版商
American Medical Association
简介
Importance
People with HIV (PWH) are often coinfected with hepatitis B virus (HBV) and/or hepatitis C virus (HCV), leading to increased risk of developing hepatocellular carcinoma (HCC), but few cohort studies have had sufficient power to describe the trends of HCC incidence and risk among PWH in the combination antiretroviral therapy (cART) era.
Objective
To determine the temporal trends of HCC incidence rates (IRs) and to compare rates by risk factors among PWH in the cART era.
Design, Setting, and Participants
This cohort study used data from the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) study, which was conducted between 1996 and 2015. NA-ACCORD pooled individual-level data from 22 HIV clinical and interval cohorts of PWH in the US and Canada. PWH aged 18 years or older with available CD4 cell counts and HIV RNA data were enrolled. Data analyses …
学术搜索中的文章
J Sun, KN Althoff, Y Jing, MA Horberg, K Buchacz… - JAMA network open, 2021
