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Industry 4.0 allows both customization and virtualization through different domains. Its practices permit industries and other sectors to become service providers. Health 4.0 customers comprise patients in addition to caretakers (both formal and non-formal) with increasing individualization and personalization as a client service. This work investigates the Health 4.0 framework. This standard involves the applicability and scalability of Industry 4.0 to healthcare and pharmaceutical domains. The manufacturing and deployment of health-oriented items must address the design practices and technology. Concepts like cloud computing, smart use of green energy, big data, new wireless networks forms and the Internet of Things (IoT). Such apply to small Cyber-Physical Systems (CPSs) related to the healthcare industry and Ambient Assisted Living (AAL). Concrete applications include Body Area Networks and other sensors and actuators networks for smart disease administration and control platforms with either different types of feedback including people, smart devices and wearables. Healthcare corporations will have to interact with governmental agencies, databases, patients, and caretakers.