作者
Srinivasan Damodharan, Gerard Marshall Raj, M Sakthibalan, Karthikeyan Dakshinamoorthy, P Muraliswaran
发表日期
2021/8
期刊
Irish Journal of Medical Science (1971-)
卷号
190
页码范围
1213-1217
出版商
Springer International Publishing
简介
Background
Long-term usage of acid suppression drugs like proton pump inhibitors (PPIs) or H2 receptor blockers in the elderly population has been found to result in vitamin B12 deficiency. However, the reports are equivocal.
Objective
To determine the serum vitamin B12 levels in elderly patients under chronic acid suppression therapy.
Methods
Patients aged above 60 years and on any of the PPIs or H2 blockers for at least 6 months were recruited. Out of 77 patients recruited, 60 patients were included for the final analysis. The serum vitamin B12 levels were measured using the AccuDiag™-Vitamin B12 ELISA system.
Results
Out of 60 patients, pantoprazole (40%) and omeprazole (37%) were the commonly prescribed acid-suppressing drugs. Nearly 50% of the patients on …
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S Damodharan, GM Raj, M Sakthibalan… - Irish Journal of Medical Science (1971-), 2021