作者
Geoffroy Rambaud, Vicky Mai, Camille Motreff, Olivier Sanchez, Pierre-Marie Roy, Yannick Auffret, Raphael Le Mao, Frédéric Gagnadoux, Nicolas Paleiron, Jeannot Schmidt, Jean Pastre, Michel Nonent, Cécile Tromeur, Pierre-Yves Salaun, Patrick Mismetti, Philippe Girard, Karine Lacut, Catherine A Lemarié, Guy Meyer, Christophe Leroyer, Grégoire Le Gal, Laurent Bertoletti, Francis Couturaud
发表日期
2023/11/1
期刊
Thrombosis Research
卷号
231
页码范围
58-64
出版商
Pergamon
简介
Background
The prevalence of pulmonary embolism (PE) is approximately 11–17 % in patients with an acute exacerbation of chronic obstructive pulmonary disease (AE-COPD). The optimal diagnostic strategy for PE in these patients remains undetermined.
Aims
To evaluate the safety and efficacy of standard (revised Geneva and Wells PE scores combined with fixed D-dimer cut-off) and computed tomography pulmonary angiogram (CTPA)-sparing diagnostic strategies (ADJUST-PE, YEARS, PEGeD, 4PEPS) in patients with AE-COPD.
Method
Post-hoc analyses of data from the multicenter prospective PEP study were performed. The primary outcome was the diagnostic failure rate of venous thromboembolism (VTE) during the entire study period. Secondary outcomes included diagnostic failure rate of PE and deep venous thrombosis (DVT), respectively, during the entire study period and the number of CTPA needed …
学术搜索中的文章
G Rambaud, V Mai, C Motreff, O Sanchez, PM Roy… - Thrombosis Research, 2023