作者
Raymond W Lam, Sidney H Kennedy, Sophie Grigoriadis, Roger S McIntyre, Roumen Milev, Rajamannar Ramasubbu, Sagar V Parikh, Scott B Patten, Arun V Ravindran
发表日期
2009/10/1
来源
Journal of affective disorders
卷号
117
页码范围
S26-S43
出版商
Elsevier
简介
BACKGROUND
In 2001, the Canadian Psychiatric Association and the Canadian Network for Mood and Anxiety Treatments (CANMAT) partnered to produce evidence-based clinical guidelines for the treatment of depressive disorders. A revision of these guidelines was undertaken by CANMAT in 2008–2009 to reflect advances in the field.
METHODS
The CANMAT guidelines are based on a question–answer format to enhance accessibility to clinicians. An evidence-based format was used with updated systematic reviews of the literature and recommendations were graded according to Level of Evidence using pre-defined criteria. Lines of Treatment were identified based on criteria that included Levels of Evidence and expert clinical support. This section on “Pharmacotherapy” is one of 5 guideline articles.
RESULTS
Despite emerging data on efficacy and tolerability differences amongst newer antidepressants …
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