作者
Franziska Hufsky, Kevin Lamkiewicz, Alexandre Almeida, Abdel Aouacheria, Cecilia Arighi, Alex Bateman, Jan Baumbach, Niko Beerenwinkel, Christian Brandt, Marco Cacciabue, Sara Chuguransky, Oliver Drechsel, Robert D Finn, Adrian Fritz, Stephan Fuchs, Georges Hattab, Anne-Christin Hauschild, Dominik Heider, Marie Hoffmann, Martin Hölzer, Stefan Hoops, Lars Kaderali, Ioanna Kalvari, Max Von Kleist, Renó Kmiecinski, Denise Kühnert, Gorka Lasso, Pieter Libin, Markus List, Hannah F Löchel, Maria J Martin, Roman Martin, Julian Matschinske, Alice C McHardy, Pedro Mendes, Jaina Mistry, Vincent Navratil, Eric P Nawrocki, Áine Niamh O’toole, Nancy Ontiveros-Palacios, Anton I Petrov, Guillermo Rangel-Pineros, Nicole Redaschi, Susanne Reimering, Knut Reinert, Alejandro Reyes, Lorna Richardson, David L Robertson, Sepideh Sadegh, Joshua B Singer, Kristof Theys, Chris Upton, Marius Welzel, Lowri Williams, Manja Marz
发表日期
2021/3
来源
Briefings in bioinformatics
卷号
22
期号
2
页码范围
642-663
出版商
Oxford University Press
简介
SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel virus of the family Coronaviridae. The virus causes the infectious disease COVID-19. The biology of coronaviruses has been studied for many years. However, bioinformatics tools designed explicitly for SARS-CoV-2 have only recently been developed as a rapid reaction to the need for fast detection, understanding and treatment of COVID-19. To control the ongoing COVID-19 pandemic, it is of utmost importance to get insight into the evolution and pathogenesis of the virus. In this review, we cover bioinformatics workflows and tools for the routine detection of SARS-CoV-2 infection, the reliable analysis of sequencing data, the tracking of the COVID-19 pandemic and evaluation of containment measures, the study of coronavirus evolution, the discovery of potential drug targets and development of therapeutic strategies. For each tool, we …
学术搜索中的文章
F Hufsky, K Lamkiewicz, A Almeida, A Aouacheria… - Briefings in bioinformatics, 2021