作者
Janelle E Bender, Anuj J Kapadia, Amy C Sharma, Georgia D Tourassi, Brian P Harrawood, Carey E Floyd Jr
发表日期
2007/10
期刊
Medical physics
卷号
34
期号
10
页码范围
3866-3871
出版商
American Association of Physicists in Medicine
简介
Neutron stimulated emission computed tomography (NSECT) is being developed to noninvasively determine concentrations of trace elements in biological tissue. Studies have shown prominent differences in the trace element concentration of normal and malignant breast tissue. NSECT has the potential to detect these differences and diagnose malignancy with high accuracy with dose comparable to that of a single mammogram. In this study, NSECT imaging was simulated for normal and malignant human breast tissue samples to determine the significance of individual elements in determining malignancy. The normal and malignant models were designed with different elemental compositions, and each was scanned spectroscopically using a simulated neutron beam. The number of incident neutrons was varied from 0.5 million to 10 million neutrons. The resulting gamma spectra were evaluated through receiver …
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