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Limb amputation can cause severe functional disability for the performance of activities of daily living. Previous studies have found differences in cognitive demands imposed by prosthetic devices due to variations in their design. The objectives of this article were to 1) identify the range of cognitive workload (CW) assessment techniques used in prior studies comparing different prosthetic devices, 2) identify the device configurations or features that reduced CW of users, and 3) provide guidelines for designing future prosthetic devices to reduce CW. A literature search was conducted using Compendex, Inspec, Web of Science, Proquest, IEEE, Engineering Research Database, PubMed, Cochrane, and Google Scholar. Forty-three studies met the inclusion criteria. Findings suggested that CW of prosthetic devices was assessed using physiological, task performance, and subjective measures. However, due to the …