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Previous studies have found that electromyography (EMG)-based prosthetic devices provide higher grasping force, increase functional performance, and have greater range of motion over conventional prostheses. However, cognitive workload (CW) is still one of the issues that can negatively affect device usability and satisfaction. In order to evaluate CW of prosthetic devices early in the design cycle, it is first necessary to select the most appropriate measures. Therefore, the objectives of this study were to: (1) review the CW measurement techniques used in prior EMG-based prosthetic device evaluations; and (2) provide guidelines to select the most appropriate measurement techniques. The findings suggested that cognitive performance models (CPM), subjective measures, task performance measures, and some physiological measures were sensitive in detecting CW differences among prosthetic device …