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Effective integration across policy domains and between spatial scales is indispensable in dealing with the inherently complex process of policy formulation and implementation at all levels. In this paper, we examine the key features of Ghana’s spatial planning system focusing on the mechanisms and challenges of policy integration in practice. We show that a combination of path dependence and recent reforms has inevitably created two distinctly separate planning systems: an established Development Planning System and a newly instituted Spatial Planning System. Under the established notion of the ‘spatial’ being distinctively separate from the ‘socio-economic’ in planning, these two systems deploy separate institutional and legal arrangements as well as policy instruments to accomplish the task of planning. Within this context, mechanisms to ensure effective policy integration were found to be weak …