作者
Edward Burn, Alexander D Liddle, Thomas W Hamilton, Andrew Judge, Hemant G Pandit, David W Murray, Rafael Pinedo-Villanueva
发表日期
2018/4/1
期刊
BMJ open
卷号
8
期号
4
页码范围
e020977
出版商
British Medical Journal Publishing Group
简介
Objectives
To assess the value for money of unicompartmental knee replacement (UKR) compared with total knee replacement (TKR).
Design
A lifetime Markov model provided the framework for the analysis.
Setting
Data from the National Joint Registry (NJR) for England and Wales primarily informed the analysis.
Participants
Propensity score matched patients in the NJR who received either a UKR or TKR.
Interventions
UKR is a less invasive alternative to TKR, where only the compartment affected by osteoarthritis is replaced.
Primary outcome measures
Incremental quality-adjusted life years (QALYs) and healthcare system costs.
Results
The provision of UKR is expected to lead to a gain in QALYs compared with TKR for all age and gender subgroups (male: <60 years: 0.12, 60–75 years: 0.20, 75+ years: 0.19; female: <60 years: 0.10, 60–75 years: 0.28, 75+ years: 0.44) and a reduction in costs (male: <60: £−1223, 60 …
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E Burn, AD Liddle, TW Hamilton, A Judge, HG Pandit… - BMJ open, 2018