作者
Edward Burn, Xintong Li, Kristin Kostka, Henry Morgan Stewart, Christian Reich, Sarah Seager, Talita Duarte‐Salles, Sergio Fernandez‐Bertolin, María Aragón, Carlen Reyes, Eugenia Martinez‐Hernandez, Edelmira Marti, Antonella Delmestri, Katia Verhamme, Peter Rijnbeek, Scott Horban, Daniel R Morales, Daniel Prieto‐Alhambra
发表日期
2022/5
期刊
Pharmacoepidemiology and Drug Safety
卷号
31
期号
5
页码范围
495-510
出版商
John Wiley & Sons, Inc.
简介
Background: Thrombosis with thrombocytopenia syndrome (TTS) has been reported among individuals vaccinated with adenovirus-vectored COVID-19 vaccines. In this study, we describe the background incidence of non-vaccine induced TTS in six European countries.
Methods: Electronic medical records from France, the Netherlands, Italy, Germany, Spain, and the United Kingdom informed the study. Incidence rates of cerebral venous sinus thrombosis (CVST), splanchnic vein thrombosis (SVT), deep vein thrombosis (DVT), pulmonary embolism (PE), and myocardial infarction or ischemic stroke, all with concurrent thrombocytopenia, were estimated among the general population of persons in a database between 2017 and 2019. A range of additional potential adverse events of special interest for COVID-19 vaccinations were also studied in a similar manner.
Findings: A total of 38 611 617 individuals were …
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E Burn, X Li, K Kostka, HM Stewart, C Reich, S Seager… - Pharmacoepidemiology and Drug Safety, 2022