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A subspace-based blind method is proposed for estimating the channel responses of a multiuser and multiantenna orthogonal frequency division multiplexing (OFDM) uplink system. It gives estimations to all channel responses subject to a scalar matrix ambiguity and does not need precise channel order information (only an upper bound for the orders is required). Furthermore, the scalar ambiguity matrix can be easily resolved by using only one pilot OFDM block, given that the number of users is smaller than the number of symbols in the pilot symbol block. Equalization methods are discussed based on the estimated channels. By using partial knowledge of the channels, a multipath subspace method is proposed that reduces the computational complexity. Simulations show that the methods are effective and robust.