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Intersection crashes are among the most frequent and lethal crash modes in the United States. Accounting for over one-third of all intersection crashes, straight crossing path (SCP) crashes are the most common intersection crash mode. Intersection Advanced Driver Assistance Systems (I-ADAS) have the potential to prevent SCP crashes by detecting imminent collisions and either alerting the driver and/or taking autonomous crash avoidance action. The objective of this study was to estimate how many SCP intersection crashes could be potentially prevented in the U.S. if every vehicle was equipped with I-ADAS. Three steps were performed in this study. First, a simulation case set was generated from 459 real world SCP intersection crashes collected as part of NHTSA's National Motor Vehicle Crash Causation Survey (NMVCCS) database. Second, the pre-crash kinematics of each vehicle was reconstructed using …