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Supply chains are prone to several operational and disruption risks. In order to design a resilient supply chain network capable of responding to such potential risks suitably, this paper proposes a novel framework for the business continuity-inspired resilient supply chain network design (BCRSCND) problem, which includes three steps. First, four resilience dimensions including Anticipation, Preparation, Robustness, and Recovery are considered to quantify the resilience score of each facility using a multi-criteria decision-making technique and considering a comprehensive set of resilience strategies. In the second step, the critical processes and their business continuity metrics (which are vital for supply chain continuity), are identified. The outputs of the first two steps provide the inputs of a novel two-stage mixed possibilistic-stochastic programing (TSMPSP) model. The model aims to design a multi-echelon, multi …