作者
Julia Kimondo, Peggoty Mutai, Peter Njogu, Charles Kimwele
发表日期
2019/4/1
期刊
Free Radicals and Antioxidants
卷号
9
期号
1
页码范围
29-34
简介
Objectives
Many plants used in ethnomedicinal interventions have anti-inflammatory, antibacterial, antiviral, anti-aging and anticancer activities attributed to their antioxidant properties. The antioxidant properties may be attributed to high polyphenol content of the plants. The Ilkisonko Maasai are a pastoralist community from Kenya known to ingest certain select plant decoctions for prevention or treatment of targeted illnesses. This study evaluated the antioxidant properties of organic and aqueous extracts of these select plants.
Methods
The antioxidant potential was evaluated by 1, 1-diphenyl-2-picrylhydrazyl free radical (DPPH) scavenging method. Total phenolic and flavonoid content were determined using the Folin–Ciocalteu’s assay and aluminium chloride colorimetric test, respectively.
Results
The organic extracts had significantly higher phenolic and flavonoid content than the aqueous extracts except for Pappea capensis in which the converse was observed. Among the studied plant extracts, Acacia nilotica had the highest phenolic content in the methanol and water extracts (237.26±1.83 mg and 149.66±0.60 mg tannic acid equivalent/g of extract) and the highest antioxidant activity in both the methanol and water extracts with an IC 50 of 54.61 μg/mL and 102.96 μg/mL, respectively. The standard, ascorbic acid, had an IC 50 of 50.32 μg/mL. In both the methanol and water extracts, Acacia reficiens had the highest flavonoid content (130.62±1.78 and 99.80±1.73 mg catechin equivalents/g of extract, respectively). The correlation between the total phenolic content and antioxidant activity was statistically significant (Pearson’sr=-0.841 …
引用总数
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