作者
Uttara Partap, Sophie H Allcock, Edyth Parker, Deepti Gurdasani, Elizabeth H Young, Manjinder S Sandhu
发表日期
2018/1
来源
Global health, epidemiology and genomics
卷号
3
页码范围
e18
出版商
Cambridge University Press
简介
BackgroundRecent research implicates antibiotic use as a potential contributor to child obesity risk. In this narrative review, we examine current observational evidence on the relation between antibiotic use in early childhood and subsequent measures of child body mass.MethodsWe searched PubMed, Web of Science and the Cochrane Library to identify studies that assessed antibiotic exposure before 3 years of age and subsequent measures of body mass or risk of overweight or obesity in childhood.ResultsWe identified 13 studies published before October 2017, based on a total of 6 81 332 individuals, which examined the relation between early life antibiotic exposure and measures of child body mass. Most studies did not appropriately account for confounding by indication for antibiotic use. Overall, we found no consistent and conclusive evidence of associations between early life antibiotic use and later child …
引用总数
2019202020212022202312521
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